Perspectives of Proteomics in Respiratory Allergic Diseases

نویسندگان

چکیده

Proteomics in respiratory allergic diseases has such a battery of techniques and programs that one would almost think there is nothing impossible to find, invent or mold. All the resources we document here are involved solving problems diseases, both diagnostic prognostic treatment, immunotherapy development. The main perspectives, according this version, three strands and/or lockout immunological system: (1) Blocking diapedesis cells involved, (2) Modifications blocking paratopes epitopes being understood by modifications antibodies, antagonisms, them, (3) FcεRI high-affinity receptors prevent specific IgEs from sticking mast basophils. These tools targets landscape are, our view, prospects field. However, still many allergens identify, including some homologies between cross-reactions, through identification structures epitopes. current vision using proteomics for purpose remains constant; also true basis controlled systems immunotherapy. Ours an open proposal use treatment.

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2023

ISSN: ['1661-6596', '1422-0067']

DOI: https://doi.org/10.3390/ijms241612924